Skin aging also impacts the cutaneous nervous system, causing a progressive loss of sensitivity that contributes to the skin’s functional aging.
SYNATIS™, an eco-responsible extract of Isatis tinctoria cultivated and elicited via precision indoor farming, combats "neuro-aging" by reconnecting the skin to its environment, thereby restoring its trophicity.
Rich in sinapic acid thanks to our ELITE™ elicitation technology—known for its neuroprotective properties—SYNATIS™ stimulates neurite outgrowth in aged cutaneous neurons in vitro. It also re-establishes the expression of key mechanosensitive channels, such as PIEZOs and TRPV4, restoring the sensory feedback and essential for maintaining skin architecture.
Ex vivo, SYNATIS™ improves the structural organization and mechanical properties of collagen—hallmarks of youthful skin—ultimately delivering a clinically visible reduction in wrinkles and a boost of firmness and elasticity. By restoring skin sensorial intelligence, SYNATIS™ clinically improves pleasant sensations and skin well-being.
