More than 100 in vitro studies to evaluate the following biomarkers:
- Extracellular matrix proteins (collagens, elastin...).
- mRNA gene expression (SOD1, CAT, GPx1, NRF2…)
- Glutathione levels (GSH-GSSG)
- Reactive Oxygen/Nytrogen Species (ROS and RNS)
- Cell cytotoxicity and proliferation (MTT, BrdU, NRU)
- Epidermal differentiation biomarkers (filaggrin, involucrin…)
- Barrier function biomarkers (hyaluronic acid, ceramides…)
- Wound-healing (Scratch-assay)
- Epidermal cohesion
- Cell proliferation
- Hair growth/loss
